at Incyte Corporation in Wilmington, Delaware, United States
Incyte is a biopharmaceutical company focused on the discovery, development, and commercialization of novel medicines to meet serious unmet medical needs in oncology and inflammation and autoimmunity. Incyte is committed to the rigorous pursuit of research and development excellence to improve the lives of patients, make a difference in health care, and build sustainable value.
The Company strives to discover and develop first-in-class and best-in-class medicines-advancing a diverse portfolio of large and small molecules.
As part of our continued investment in discovery research, we are currently seeking a cell biologist to contribute to early drug discovery projects in oncology and immunology. The candidate will be responsible for designing, developing and validating novel cell based assays to support lead finding (biologics and small molecules). The successful candidate will work closely with scientists from the technology, pharmacology, chemistry, and biologics groups at the interface of transitioning new targets into full discovery programs. A solid understanding of cancer cell biology and/or immunology as well as knowledge and experience with a variety of cell based assay formats including endpoint and phenotypic assays is required.
Design, execute, and interpret cell-based in vitro experiments for small and large molecule discovery
Culture of cell lines and isolation and culture of human PBMCs
Perform multicolor flow cytometry experiments for immune cell phenotyping and functional assessment
Analyze data, prepare reports and presentations for internal and external meetings
Work collaboratively across multiple functional groups within drug discovery to achieve key goals
Miniaturize and adapt cell-based assays to automated screening systems
Bachelor or Master in immunology, immuno-oncology or a related field
Expertise in the following techniques: multicolor flow cytometry (BD cytometers), magnetic cell isolation, cell culture, immune cell phenotyping, ELISA, MSD, MLR, and cytotoxicity assays
Familiarity with liquid handling instrumentation is a plus
Effective communication and presentation skills and willingness to collaborate with different functional groups is essential
We appreciate, celebrate, and thrive on one another’s differences and strengths and are proud to be an Equal Opportunity Employer. By valuing diversity of backgrounds and perspectives and prohibiting all forms of harassment, we are able to promote a collaborative and innovative work environment in which everybody can contribute to their fullest potential.