Research Scientist - Gene Therapy w/Sign--On Bonus

at Christiana Care Health System in Newark, Delaware, United States

Job Description

ChristianaCare's Gene Editing Institute (GEI) is advancing the science of gene editing with one goal: accelerating cures for disease and improving treatments for all people through discovery, translational science and education. We are a worldwide leader in CRISPR gene editing technology!

The institute is rapidly growing, and we're searching for Research Scientists to join the innovative team elucidating the mechanism of CRISPR-directed gene editing in human cells.

With direct guidance from the Executive Director of the Gene Editing Institute and the Discovery Research Group Leader, you will participate in projects focusing on the identification of new gene editing tools with a specific focus on expansion of the CRISPR/Cas gene editing portfolio. In addition, your work will be centered on elucidating the regulatory circuitry that surrounds CRISPR-directed gene editing in human somatic and progenitor cells.

The Research Scientist will be expected to work independently on the design and execution of molecular and cellular experimentation in the state-of-art facility, and assessment of results statistically and computationally. Experience in the cultivation of iPSCs/progenitor cells and/or protein purification and characterization will be considered a plus in the evaluation process.

Additional Duties Include:

Present research findings, including preparation of research reports and abstracts, dissemination at national and international scientific conferences and publication of manuscripts by peer-reviewed scientific journals.

Contribute to the conception design and writing of research grants to obtain outside funding in support of research protocols and performs literature reviews and searches. The successful candidate will initially serve as scope principal investigator with the possibility of evolving into an independent researcher in the Gene Editing Institute

Maintain laboratory notebook containing laboratory protocols used and results derived for each experiment, carefully organized and ordered by project and date and keeps highly technical records of all experiments.

Qualified Candidates will possess:

PhD in medical and molecular biology, biochemistry, cell biology, or a closely related field with 0 - 4 year experience OR

Masters with 2 - 6 year experience in medical and molecular biology, biochemistry, cell biology, or a closely related field

Candidates should have authored at least two first author publication in reputable journals; In vitro and in vivo CRISPR research experience are a plus but familiarity with molecular biology and cell techniques are critical.

This position involves direct experimentation, bench work, centered on the discovery of novel gene editing systems and there are application in human and mammalian cells.

First-hand or familiarity with CRISPR/Cas9/Cas12a/Cas13s gene editing systems.

Knowledge in mechanistic aspects of DNA repair and recombination pathways in human cells.

Experience in research methodology, principles and procedures

About ChristianaCare:
ChristianaCare is the one of the Mid Atlantic's largest academic health care providers and consists of 3 campuses: Wilmington, Newark and Union at Cecil County. Through our values of love and excellence, ChristianaCare is consistently identified as a regional center of excellence for cardiology, cancer and women's health services and ranked by US News & World as Best Hospital.

EEO Statement:
UPDATE: ChristianaCare is committed to prioritizing the health and safety of our patients and caregivers. As we continue to meet the needs of our caregivers and our community through the COVID-19 pandemic, our commitment to health and safety requires that we take new steps to ensure a safe environment for medical care for our patients and a workplace that avoids preventable harm for our caregivers. For this reason, vaccination for COVID-19 is required for all caregivers at ChristianaCare and is considered a safety standard that is job-related and consistent with business necessity for all caregivers.

Christiana Care Health System is an equal opportunity employer, firmly committed to prohibiting discrimination, whose staff is reflective of its community, and considers qualified applicants for open positions without regard to race, color, sex, religion, national origin, sexual orientation, genetic information, gender identity or expression, age, veteran status, disability, pregnancy, citizenship status, or any other characteristic protected under applicable federal, state, or local law.

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Job Posting: 897751

Posted On: Jan 15, 2022

Updated On: Feb 14, 2022