Executive Director, Inflammation & Auto Immunity

at Incyte Corporation in Wilmington, Delaware, United States

Job Description

Incyte is a biopharmaceutical company focused on the discovery, development, and commercialization of novel medicines to meet serious unmet medical needs in oncology and inflammation and autoimmunity. Incyte is committed to the rigorous pursuit of research and development excellence to improve the lives of patients, make a difference in health care, and build sustainable value.

The Company strives to discover and develop first-in-class and best-in-class medicines-advancing a diverse portfolio of large and small molecules.

Job Summary (Primary function)

The Executive Director, IAI Pharmacology is primarily responsible for the scientific and strategic leadership of Incyte's growing Inflammation & Autoimmunity (IAI) drug discovery portfolio. Additionally, the role requires hands-on direction, guidance and oversight of all aspects of preclinical drug discovery activities within the research team. The candidate will also have the opportunity to work closely with the immuno-oncology teams and is expected to develop and sustain productive working relationships across the enterprise. A critical aspect of the role is to leverage effectively internal and external (academia, CRO) pharmacology capabilities to enable regulatory filings (IND, NDA etc.) and to foster a collaborative research environment with internal functions including the clinical development team. The successful candidate will be an outstanding scientist with expertise in all aspects of molecular and cellular immunology together with experience in contemporary drug discovery obtained in a biotech or pharma environment. A demonstrated record of success in target identification, validation and prosecution of drug discovery campaigns is strongly preferred.

Essential Functions of the Job (Key responsibilities)


Work closely with the CSO, define, implement and execute a scientifically strong, competitive and compelling research strategy for the IAI discovery team


Ensure effective collaboration with other functions in the discovery and clinical development departments.


Provide hands-on leadership and critical oversight of all preclinical laboratory activities evaluating novel investigational agents.


Coordinate the activities of an extensive and global network of CRO partners and academic collaborators to ensure close alignment with Incyte program objectives


Effectively lead and enable the career development all IAI research personnel


Act as the scientific lead for in-licensing and business development activities, key external expert (KEE) interactions, medical affairs and commercial functions


Manage departmental budget(s) and act as the primary cost center owner.


As needed, provide investor interaction content including drafting Q&As and materials for face-to-face meetings etc.

Qualifications (Minimal acceptable level of education, work experience, and competency)


Ph.D. in Immunology or a related field with deep experience in molecular/cell biology and in vivo immune pharmacology.


10+ years post-doctoral experience of drug discovery in biotech / pharmaceutical industry.


Post-doctoral experience in a relevant field.


Demonstrated record of accomplishment of applying scientific knowledge to design and execute a successful research strategy.


Supervisory and research team leadership experience.


Knowledge of dermatological diseases advantageous.


Expertise in flow cytometry, transcriptomic and proteomic analysis essential.


Excellent communication skills.


Extensive evidence of scientific excellence via a peer-reviewed publication record.

Disclaimer: The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications. Management reserves the right to change or modify such duties as required.

Incyte Corporation is committed to creating a diverse environment and is proud to be an equal opportunity employer.

We Respect Your Privacy

Learn more at:

The Incyte hiring organization processes your personal data to manage your job application in order to enter into an employment relationship with you if you are the successful candidate.


During the process, you may be asked to respond to questions that will screen out your application if you do not meet certain objective criteria required by the job. You can learn more about this process .

You may have the right to access, delete, restrict, edit, move, or object to the use of your personal data. You may... For full info follow application link.


We appreciate, celebrate, and thrive on one another’s differences and strengths and are proud to be an Equal Opportunity Employer. By valuing diversity of backgrounds and perspectives and prohibiting all forms of harassment, we are able to promote a collaborative and innovative work environment in which everybody can contribute to their fullest potential.        



Copy Link

Job Posting: 881007

Posted On: Dec 05, 2021

Updated On: Jan 04, 2022