DMPK - Staff Scientist I

in New Castle County, DE

Job Description

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Principal responsibilities of an Staff Scientist in QPS’ DMPK in vivo department may include: working under the direction of a Principal Investigator to perform wet lab experiments; sample preparation by various extraction methods; and analysis of drug and metabolites in biological samples to support preclinical drug discovery and metabolism programs.  As a senior analyst, should be able to plan a study, organize notebooks and review and comment on project-related sections of draft reports.


Essential Functions

  • Independently perform animal dosing, biological sample collections, sample analysis, and sample storage for studies (PK, mass balance, whole-body (WBA) and micro autoradiography.
  • Organize experimental data, perform data processing and draw conclusions.
  • Perform data analysis and maintain study records.
  • Evaluate significance of data and report findings.
  • Assess the quality and integrity of the data generated by instruments such as mass spectrometers, liquid scintillation counters, etc.
  • Communicate with PI/senior staff regarding study events and results.
  • Perform routine lab operations, such as sample extraction, preparing reagents, pipette, weigh, monitor, record and replenish supplies, in a neat/clean manner.
  • Document results and accurately record observations in accordance with GLPs and SOPs.
  • Assist in summarizing data, including verification/QC review of study data, notebooks, and study reports.



  • Demonstrated proficiency at operating relevant laboratory equipment, such as automatic sample preparation and liquid handling system 
  • Familiarity with majority of wet lab instruments/equipment.Familiarity with LIMS and databases.
  • Proficient in all extraction techniques.
  • Working knowledge of GLPs and other regulatory and safety standards.



  • Bachelor’s level or Master’s level degree in Analytical Chemistry, Biochemistry, Pharmacology or related science with 2 to 5 years of relevant experience.
  • Associate’s level degree in Analytical Chemistry, Biochemistry, Pharmacology or related science with 3 to 5 years of relevant experience.
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Job Posting: 878268

Posted On: Nov 29, 2021

Updated On: Dec 29, 2021