Research Investigator, Chemistry (DNA Encoded Libr

at Incyte Corporation in Wilmington, Delaware, United States

Job Description

Incyte is a biopharmaceutical company focused on the discovery, development, and commercialization of novel medicines to meet serious unmet medical needs in oncology and inflammation and autoimmunity. Incyte is committed to the rigorous pursuit of research and development excellence to improve the lives of patients, make a difference in health care, and build sustainable value.

The Company strives to discover and develop first-in-class and best-in-class medicines-advancing a diverse portfolio of large and small molecules.

Our Discover Chemistry group is looking for a Research Investigator. This position is responsible for the construction of DNA Encoded Libraries to support hit identification

Essential Functions of the Job (Key responsibilities)

Design and synthesis of DNA Encoded Libraries.

Independently design/conduct organic chemistry experiments to enable the synthesis of novel DNA Encoded Libraries.

Resynthesis of hits utilizing traditional synthetic organic chemistry methods to support hit validation.

Application of medicinal chemistry principles to assist in the design of drug-like libraries.

Maintain a well-documented laboratory notebook and provide suitable data for patent applications and publications.

Prepare presentations and present research results clearly to the department and other disciplines.

Qualifications (Minimal acceptable level of education, work experience, and competency)

Master's degree in Organic Chemistry with proven experience in combinatorial chemistry (experience with DNA Encoded Library technology is a plus) or Ph.D. in Organic Chemistry with practical experience in the area of DNA Encoded Libraries.

Life-long learner: leverages extensive use of the literature to increase knowledge base in all aspects of medicinal and organic chemistry.

Follows the safety rules and maintains a safe working environment.

Team player: able to work with others in their group, department and company towards the common goal of inventing novel medicines. Positively influences the culture of the group.


Disclaimer: The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications. Management reserves the right to change or modify such duties as required.

Incyte Corporation is committed to creating a diverse environment and is proud to be an equal opportunity employer.

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We appreciate, celebrate, and thrive on one another’s differences and strengths and are proud to be an Equal Opportunity Employer. By valuing diversity of backgrounds and perspectives and prohibiting all forms of harassment, we are able to promote a collaborative and innovative work environment in which everybody can contribute to their fullest potential.        



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Job Posting: 849669

Posted On: Sep 27, 2021

Updated On: Oct 27, 2021