Associate Director, Bioinformatics

at Incyte Corporation in Wilmington, Delaware, United States

Job Description

Incyte is a biopharmaceutical company focused on the discovery, development, and commercialization of novel medicines to meet serious unmet medical needs in oncology and inflammation and autoimmunity. Incyte is committed to the rigorous pursuit of research and development excellence to improve the lives of patients, make a difference in health care, and build sustainable value.

Translational Sciences at Incyte has been established to bridge the research findings at the Discovery and Development levels within each of our clinical programs. In collaboration with academic, clinical and industry scientists, this group develops knowledge around each of our existing programs to enable clinical evaluation of target modulation, biological changes that correlate with target modulation, as well as biomarkers or patient characteristics that could be utilized to predict response to therapy. The results are used to enrich and refine the Development program strategy as well as inform and guide future Discovery efforts.

The Bioinformatics group within the Translational Sciences department at Incyte is seeking an individual with >10 years of post-graduate training, demonstrated leadership skills with expertise in the fields of molecular biology, cell biology, oncology or immunology along with experience in using computational approaches to address complex biological questions.

Incyte is focused on developing therapies for cancer and inflammatory diseases, and the individual will lead translational approaches that enable human clinical studies. We are looking for a highly motivated scientist to work in a collaborative environment focused on pushing the boundaries of science in the context of making new medicines. The position is located in Wilmington DE, with easy access to major east coast cities.

Job Summary (Primary function)

The Associate Director/Director, Bioinformatics develops methods for working with the program leads to analyze complex biological data sets from different translational platforms.

Essential Functions of the Job (Key responsibilities)


Function as a scientific thought leader within the bioinformatics group and wider organization


Leverage omic data sets, clinical data and computational approaches to support and guide clinical development programs as well as harness these analysis to enable ongoing target discovery efforts


Collaborate with drug discovery scientists, translational scientists and clinical teams to develop translational strategies and approaches for patient selection for clinical studies


Provide technical expertise within highly collaborative environment


Utilize computational biology methods to integrate, analyze and visualize results with data sets obtained from a variety of translational platforms


Present to Company leadership and multidisciplinary audiences within the organization

Qualifications (Minimal acceptable level of education, work experience, and competency)


MD or PhD degree, or equivalent experience with >10 years of post-graduate training


Experience in molecular biology, cell biology, oncology or immunology


Demonstrated track record analyzing and visualizing omic data sets to advance drug development programs


Ability to work effectively in a highly-collaborative, multi-disciplinary environment, and manage multiple tasks and responsibilities


Exceptional verbal and written communication skills


Strong analytical skills and statistical experience


Expertise in R (e.g. Bioconductor, Tidyverse packages) for statistical analysis and visualization


Scripting language (Python, Perl) and/or other high level language (Java, C++) experience


Familiarity with relevant public clinical data sets, advanced analytical approaches, and machine learning methods


A high level of emotional intelligence and willing to work closely and collaboratively with other functional groups internal and external to the company

Disclaimer: The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications. Management reserves the right to change or modify such duties as required.

Incyte Corporation is committed to creating a diverse environment and is proud to be an equal opportunity employer.

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Job Posting: 841983

Posted On: Sep 08, 2021

Updated On: Oct 12, 2021