Sr Principal Investigator, Translational Sciences,

at Incyte Corporation in Wilmington, Delaware, United States

Job Description

Incyte is a biopharmaceutical company focused on the discovery, development, and commercialization of novel medicines to meet serious unmet medical needs in oncology and inflammation and autoimmunity. Incyte is committed to the rigorous pursuit of research and development excellence to improve the lives of patients, make a difference in health care, and build sustainable value.

The Company strives to discover and develop first-in-class and best-in-class medicines-advancing a diverse portfolio of large and small molecules.

Translational Sciences at Incyte has been established to bridge the research findings at the Discovery and Development levels within each of our clinical programs. In collaboration with academic, clinical and industry scientists, this group develops knowledge around each of our existing programs to enable clinical evaluation of target modulation, biological changes that correlate with target modulation, as well as biomarkers or patient characteristics that could be utilized to predict response to therapy. The results are used to enrich and refine the Development program strategy as well as inform and guide future Discovery efforts.

Senior/Principal Investigator Translational Bioinformatics

The Bioinformatics group within the Translational Sciences department at Incyte is seeking an individual with >4 years of post-graduate training, expertise in the fields of immune-oncology or immunology along with experience in using computational approaches to analyze and visualize genomic data sets.

Incyte is focused on developing therapies for cancer and inflammatory diseases, and the individual will lead translational approaches that enable human clinical studies. We are looking for a highly motivated scientist to work in a collaborative environment focused on pushing the boundaries of science in the context of making new medicines. The position is located in Wilmington DE, with easy access to major east coast cities.


Utilize computational biology methods to integrate, analyze and visualize results with data sets obtained from a variety of translational platforms

Analyze and interpret genome-scale NGS data sets

Identify and evaluate markers for clinical response

Provide technical expertise within highly collaborative environment

Present results of analysis to multidisciplinary audiences within the organization


Ph.D. with experience in immune-oncology or immunology preferred

Demonstrated experience in analyzing and visualizing NGS data sets

Expertise in using R or MATLAB for data visualization

Ability to work effectively in a highly-collaborative, multi-disciplinary environment, and manage multiple tasks and responsibilities

Strong analytical skills

A high level of emotional intelligence and willing to work closely and collaboratively with other functional groups internal and external to the company

Exceptional verbal and written communication skills

Incyte Corporation is committed to creating a diverse environment and is proud to be an equal opportunity employer.

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We appreciate, celebrate, and thrive on one another’s differences and strengths and are proud to be an Equal Opportunity Employer. By valuing diversity of backgrounds and perspectives and prohibiting all forms of harassment, we are able to promote a collaborative and innovative work environment in which everybody can contribute to their fullest potential.        



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Job Posting: 841071

Posted On: Sep 04, 2021

Updated On: Oct 12, 2021