at Incyte Corporation in Wilmington, Delaware, United States
Incyte is a biopharmaceutical company focused on the discovery, development, and commercialization of novel medicines to meet serious unmet medical needs in oncology and inflammation and autoimmunity. Incyte is committed to the rigorous pursuit of research and development excellence to improve the lives of patients, make a difference in health care, and build sustainable value.
The Company strives to discover and develop first-in-class and best-in-class medicines-advancing a diverse portfolio of large and small molecules.
Research Scientist / Sr. Research Scientist, Antibody Pharmacology
Job Summary (Primary function)
The successful candidate will be responsible for the hands-on execution of in vivo and in vitro cancer cell biology/immuno-oncology studies to evaluate antibody based therapeutics for treatment of cancer. This individual will work as part of a rapidly growing bio-therapeutics group focusing on new target validation and more established discovery pipeline projects. A successful candidate will be able to utilize the appropriate preclinical models to support bio-therapeutic drug development.
Essential Functions of the Job (Key responsibilities)
Execute in vitro and in vivo experiments to achieve defined objectives. Develop and/or optimize new laboratory techniques with general supervision.
Organize own work and prioritize assignments. Demonstrate scientific and technical knowledge relevant to project goals.
Collaborate with other members of the group to achieve key goals.
Interpret results, troubleshoots and solves technical issues.
Draw conclusions from experiments and begin to apply theoretical knowledge to ask pertinent questions.
Ability to effectively present research at internal / external meetings.
Perform lab support activities such as supplies ordering and lab equipment maintenance.
Qualifications (Minimal acceptable level of education, work experience, and competency)
Bachelor's degree with 3+ year of working experience in related scientific discipline is required. Master degree is preferred.
Pharmaceutical/biotechnological industry experience preferred but not necessary.
Must have good understanding of basic scientific principles and research practices in the field of cancer biology and immunology.
Experiences in immune cell isolation from whole blood (tissues or tumor dissociation is highly valuable) and experience with primary cell culture techniques.
Extensive hands-on experience developing, implementing, and running multi-color flow cytometry, familiar with flow analysis software such as FlowJo.
Designing, developing, and performing robust in vitro cell based assays that incorporate functional readouts, including activation, proliferation, cytokine production, and cytotoxicity.
Prior experiences with additional biological assays such as Western Blot, MLR, MSD, IncuCyte and ADCC/CDC, etc. is a plus.
The candidate should be proficient in data collection and documentation of study results in the form of lab notebook reports.
Excellent oral and written communication skills.
Ability to work effectively in a highly collaborative research environment.
Disclaimer: The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications. Management reserves the right to change or modify such duties as required.
Incyte Corporation is committed to creating a diverse environment and is proud to be an equal opportunity employer.
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