Research Scientist, Purification Process Science

at Incyte Corporation in Wilmington, Delaware, United States

Job Description

Incyte is a biopharmaceutical company focused on the discovery, development, and commercialization of novel medicines to meet serious unmet medical needs in oncology and inflammation and autoimmunity. Incyte is committed to the rigorous pursuit of research and development excellence to improve the lives of patients, make a difference in health care, and build sustainable value.

The Company strives to discover and develop first-in-class and best-in-class medicines-advancing a diverse portfolio of large and small molecules.

Our Global BioPharmaceutical Development group is seeking a motivated and dedicated protein purification and analytical scientist to support protein purification process development and optimization primarily for novel therapeutic monoclonal antibody products including bispecifics throughout all stages of clinical trials.

Essential Functions of the Job (Key responsibilities):

Conduct routine high-throughput protein purification to support cell line and cell culture development

Conduct routine analysis of in-process samples using relevant product purity and process impurity analytical tools (SE-HPLC, CEX-HPLC, SDS-PAGE, capillary gel electrophoresis, ELISA, etc.) to support purification process development

Prepare buffers and solutions needed for laboratory work

Keep electronic laboratory notebook

Manage laboratory supplies and instrument maintenance

Participate and present updates in routine group meetings

Other responsibilities as assigned

Qualifications (Minimal acceptable level of education, work experience, and competency):

BS or MS. degree in biochemistry, bioengineering, biology, chemistry or related fields, preferably with some relevant industry experiences

Good knowledge in protein chemistry and bioprocessing

Good knowledge and hands-on experiences in various types of column chromatography (affinity, size exclusion, ion exchanges, and hydrophobic interaction)

Experiences in using AKTA line of preparative purification instruments

Experiences in protein analysis such as HPLC, SDS-PAGE, capillary gel electrophoresis, ELISA, etc.

Good verbal and written communication skills

Organized, cooperative, independent, meticulous

Experiences in high-throughput protein purification and purification process development are desirable but not required.

Disclaimer: The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications. Management reserves the right to change or modify such duties as required.

Incyte Corporation is committed to creating a diverse environment and is proud to be an equal opportunity employer.

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We appreciate, celebrate, and thrive on one another’s differences and strengths and are proud to be an Equal Opportunity Employer. By valuing diversity of backgrounds and perspectives and prohibiting all forms of harassment, we are able to promote a collaborative and innovative work environment in which everybody can contribute to their fullest potential.        



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Job Posting: 823841

Posted On: Jul 17, 2021

Updated On: Aug 07, 2021