at Incyte Corporation in Wilmington, Delaware, United States
Incyte is a biopharmaceutical company focused on the discovery, development, and commercialization of novel medicines to meet serious unmet medical needs in oncology and inflammation and autoimmunity. Incyte is committed to the rigorous pursuit of research and development excellence to improve the lives of patients, make a difference in health care, and build sustainable value.
The Company strives to discover and develop first-in-class and best-in-class medicines-advancing a diverse portfolio of large and small molecules.
Contract - Sr. Research Scientist, Antibody Pharmacology
This is a 6-month temporary position where the candidate will be responsible for performing in vitro and in vivo studies for cancer immunotherapy drug discovery programs. This includes the development of relevant model systems for the identification and validation of novel therapeutic targets. The successful candidate is able to work independently and demonstrates a broad understanding of immunology and cancer biology, being able to use this knowledge to design and execute a research plan that answers critical questions about compounds and targets under evaluation.
Essential Functions of the Job
Design, execute, and interpret cell-based in vitro experiments to explore the therapeutic potential of antibodies
Develop new assays to screen functional activity of antibodies
Culture of cell lines and isolation and culture of human PBMCs
Evaluate data, prepare reports and presentations for internal and external meetings
Work collaboratively across multiple functional groups within drug discovery and clinical development to achieve key goals
Master in Immunology, Cancer Biology, Pharmacology or related field
Strong background in immunology, antibody-related functions, and oncogenic signaling pathways
Mouse work experience including in vivo models of cancer - preferred
Expertise in the following techniques is mandatory: magnetic cell isolation, cell culture, immune cell phenotyping, multicolor flow cytometry (BD cytometers), ELISA, MSD, Western blot, MLR, ADCC, basic molecular biology including isolation of nucleic acid and real-time PCR
Excellent communication skills
Disclaimer: The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications. Management reserves the right to change or modify such duties as required.
Incyte Corporation is committed to creating a diverse environment and is proud to be an equal opportunity employer.
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