Sr. Research Investigator, Clinical Pharmacokineti

at Incyte Corporation in Wilmington, Delaware, United States

Job Description

Incyte is a biopharmaceutical company focused on the discovery, development, and commercialization of novel medicines to meet serious unmet medical needs in oncology and inflammation and autoimmunity. Incyte is committed to the rigorous pursuit of research and development excellence to improve the lives of patients, make a difference in health care, and build sustainable value.

The Company strives to discover and develop first-in-class and best-in-class medicines-advancing a diverse portfolio of large and small molecules.

Job Summary (Primary function)

Sr Research/Principal Investigator, Clinical Pharmacokinetics)

This position will be responsible for performing PK/PD analysis, population PK/PD analysis and PBPK for Biologics and small molecules in clinical pharmacokinetics group.

Essential Functions of the Job (Key responsibilities)

Advise clinical teams on PK and PK/PD study design

Perform PK/PD analyses, pop PK/PD analyses, interpret and report data to clinical teams, management in a timely manner.

Conduct model based simulations using PBPK method to design studies that yield high value PK/PD information for future critical decisions.

Represent clinical pharmacokinetics on clinical project teams

Work with the clinician, biostatistician, and data manager to provide deliverables on time.

Present work at internal and external scientific meetings and publish manuscripts in peer-reviewed journals.

Qualifications (Minimal acceptable level of education, work experience, and competency)

Ph.D. in Pharmacokinetics, Pharmacometrics, Pharmacology, Engineering, Statistics or related fields.

1+ years of experience in clinical PK, population PK analysis and PBPK modeling.

Experience in analyzing clinical pharmacology data.

Experience in large molecule development is highly preferable.

Experience with a range of software packages, such as but not limited to: WinNonlin, NONMEM, R, SimCyp and GastroPlus.

Experience with writing reports for regulatory submissions is desired

Excellent written and verbal communication skills

Ability to work independently

Disclaimer: The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications. Management reserves the right to change or modify such duties as required.

Incyte Corporation is committed to creating a diverse environment and is proud to be an equal opportunity employer.

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We appreciate, celebrate, and thrive on one another’s differences and strengths and are proud to be an Equal Opportunity Employer. By valuing diversity of backgrounds and perspectives and prohibiting all forms of harassment, we are able to promote a collaborative and innovative work environment in which everybody can contribute to their fullest potential.        



Job Details


Incyte Corporation


1801 Augustine Cutoff
Wilmington, Delaware 19803
United States

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Job Posting: 809767

Posted On: Jun 03, 2021

Updated On: Jul 03, 2021