Sr. Research Investigator/Principal Investigator,

at Incyte Corporation in Wilmington, Delaware, United States

Job Description

Overview   Incyte is a biopharmaceutical company focused on the discovery, development, and commercialization of novel medicines to meet serious unmet medical needs in oncology and inflammation and autoimmunity. Incyte is committed to the rigorous pursuit of research and development excellence to improve the lives of patients, make a difference in health care, and build sustainable value. The Company strives to discover and develop first-in-class and best-in-class medicines-advancing a diverse portfolio of large and small molecules. Job Summary(Primary function) This position will provide strategic PK support to the discovery and nonclinical development of antibody drugs. The selected individual will be an integral project team member representing PK on antibody research projects to ensure effective integration of PK and PKPD into the team strategy. Essential Functions of the Job(Key responsibilities) *Serve as a PK project lead on antibody discovery project teams. Initiate and engage in multifunctional collaborations to facilitate the advancement of drug candidates and build thorough knowledge of drug candidate properties. *Be responsible for the design and interpretation of PK studies necessary for the selection of clinical candidates. *Ensure adequate PK characterization and liability assessment to support candidate nomination and clinical dose projections. *Responsible for writing PK and TK reports, and author PK sections for regulatory submissions and IB updates. *Develop interdisciplinary collaborations and ensure that key PK data, information, and priorities are integrated into overall project team strategy. Qualifications (Minimal acceptable level of education, work experience, and competency) *PhD or equivalent with 3+ years of industry experience in PK. *A strong working knowledge of antibody pharmacokinetics with hands on experience using PK software packages is preferred. Knowledge and expertise in modeling such as PBPK and PK/PD is a desirable plus. *A broad knowledge of antibody clearance mechanisms and antibody bioanalytical techniques is preferred. *Appropriate understanding of applicable FDA and European regulations with experience in IND filing and clinical protocols is a plus *Excellent oral and written communication skills are essential along with strong organizational skills. Disclaimer: The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications. Management reserves the right to change or modify such duties as required. Incyte Corporation is committed to creating a diverse environment and is proud to be an equal opportunity employer. We Respect Your Privacy Learn more at: The Incyte hiring organization processes your personal data to manage your job application in order to enter into an employment relationship with you if you are the successful candidate.   During the process, you may be asked to respond to questions that will screen out your application if you do not meet certain objective criteria required by the job. You can learn more about this process . You may have the right to access, delete, restrict, edit, move, or object to the use of your personal data. You may also have a right to report concerns to the authority responsible for data privacy in the country where the position is based or where you live or work. You can learn more about Incyte's data protection practices . By accessing this link you can learn about the types of personal data we collect, how we use it, whether collection and processing is optional, sources of the personal data we process, how it is shared, where it is stored or transferred to, how long we keep it, and contact information for Incyte, Incyte's data protection officer, and your supervisory authority (if applicable). Please contact if you have any questions or concerns or would like to exercise your rights.   We appreciate, celebrate, and thrive on one another’s differences and strengths and are proud to be an Equal Opportunity Employer. By valuing diversity of backgrounds and perspectives and prohibiting all forms of harassment, we are able to promote a collaborative and innovative work environment in which everybody can contribute to their fullest potential.  


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Job Posting: 1257908

Posted On: Apr 09, 2024

Updated On: May 09, 2024

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