at Incyte Corporation in Wilmington, Delaware, United States
Incyte is a biopharmaceutical company focused on the discovery, development, and commercialization of novel medicines to meet serious unmet medical needs in oncology and inflammation and autoimmunity. Incyte is committed to the rigorous pursuit of research and development excellence to improve the lives of patients, make a difference in health care, and build sustainable value.
The Company strives to discover and develop first-in-class and best-in-class medicines-advancing a diverse portfolio of large and small molecules.
Our Antibody Pharmacology Group is seeking a highly motivated and accomplished scientist to contribute to our efforts to bring novel medicines to patients in need. The Sr. Research/Principal Investigator is responsible for designing and performing in-vitro studies for biotherapeutic drug discovery programs. This includes developing relevant pre-clinical model systems to identify and validate novel therapeutic targets.
Essential Functions of the Job (Key responsibilities)
Independently design, execute and interpret cell-based assays for large molecule discovery.
Familiar with large molecule screening assays for exploratory and lead optimization programs.
Ability to maintain accurate and detailed records of experiments, evaluate data and prepare reports and presentations for internal meetings in a timely manner.
Develop interdisciplinary collaborations and ensure that key data, information, and priorities are integrated into the overall project team strategy.
Flexibility to acquire additional competencies and skillsets as needed.
Should be highly independent and organized, with excellent verbal and written communication skills.
Qualifications (Minimal acceptable level of education, work experience, and competency)
PhD degree in cell biology/immunology or related fields.
Experience in the ex-vivo culture of human cells, immune cell separation using magnetic beads/cell sorting, functional immune assays and flow cytometry.
Proficient in cell culture and cell-based assays for biologics screening using platforms such as ELISA, HTRF, MSD, and CTG.
Hands-on experience in flow cytometry, standard molecular biology techniques, including Western Blotting, RT-qPCR, and gene-editing techniques (RNAi, CRISPR).
Disclaimer: The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications. Management reserves the right to change or modify such duties as required.
Incyte Corporation is committed to creating a diverse environment and is proud to be an equal opportunity employer.
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