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National Cancer Institute/National Clinical Trials Network L

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Job Details
Job Order Number
JC149735677
Company Name
AstraZeneca Pharmaceuticals LP
Physical Address

Wilmington, DE 19806
Job Description

At AstraZeneca we work together across global boundaries to make an impact and find answers to challenges. We do this with the utmost integrity even in the most difficult situations because we are committed to doing the right thing. We continuously forge partnerships that help pursue world-class medicines in new ways, combining our people’s exceptional skills with those of people from all over the globe. As NCI/NCTN Lead, you will play a pivotal role in channeling our scientific capabilities to make a positive impact on changing practice and patients’ lives.

AstraZeneca’s vision in Oncology is to help patients by redefining the cancer-treatment paradigm, with the aim of bringing six new cancer medicines to patients between 2013 and 2020. A broad pipeline of next-generation medicines is focused principally on four disease areas – breast, ovarian, lung and hematological cancers. As well as other tumor types, these are being targeted through five key platforms – immunotherapy, the genetic drivers of cancer and resistance, DNA damage repair, HER2 and antibody drug conjugates, underpinned by personalized healthcare and biomarker technologies.

The NCI/NCTN Lead will be a member of the External Alliances team within US Medical Affairs Oncology, and will report to the Head of US External Alliances. The vision of the External Alliances team is to maximize the value of our portfolio and above brand strategy, further our scientific leadership, and deliver on AstraZeneca’s bold ambition in Oncology. We deliver on this vision by focusing on key activities with regards to evidence generation, quality care, and education with key groups of external stakeholders that include the NCI and National Clinical Trials Network (NCTN) Groups and Foundations.

Position Summary: NCI/NCTN Lead

The NCI/NCTN Lead will be responsible for building trusted relationships with NCI, NCTN Groups, and NCTN Foundations. The Lead will be responsible for coordinating activity related to select clinical trials studying AZ investigational products under programs including with the Cancer Therapies Evaluation Program (CTEP) via Cooperative research and development agreements (CRADAs) and the NCI Experimental Therapeutics (NExT) initiatives.

The Lead will work closely with US Medical Affairs Core Medical Teams (Medical Leads, Medical Directors) and other stakeholders, colleagues from across the AZ Oncology division including R&D to understand areas of research interest and key evidence gaps. This will enable the Lead to develop and execute integrated evidence generation and engagement strategies for the NCI and NCTN groups that address AZ’s Oncology priorities, ultimately for the improvement of the lives of cancer patients.

Core Responsibilities

+ Develop plans for selective, strategic clinical trial activity that are closely aligned with Medical Affairs External Sponsored Research and overall Evidence Generation strategies for US Oncology.

+ Organize and enable joint AZ/NCI Steering Committee to provide greater internal transparency, coordination and external collaboration execution.

+ Possess and maintain knowledge and awareness of the leadership, capabilities, and research performance of NCI and NCTN Groups and Foundations.

+ Possess and maintain an understanding of the NCI/NCTN landscape and operations.

+ Engage regularly with Core Medical Teams and R&D Teams across AZ Oncology to ensure timely updates on relevant NCI/NCTN evidence generation activities.

+ Liaise with internal operational stakeholders (e.g. ESR Delivery Directors and Managers; NCI Operations Alliance Director; Contracting; Legal) to rapidly contract for approved studies and address operational issues.

+ Coordinate with field medical colleagues on activity with individual centers and investigators.

Internal Contacts/Customers

+ Core Medical Teams, including Franchise Heads, Medical Leads and Medical Directors

+ US External Sponsored Research Team

+ US Site Management and Monitoring Team

+ Clinical Development and Regulatory Affairs

+ Global Medical Affairs and Global Product Teams

+ Medical Science Liaisons and Regional Directors

External Contacts/Customers

+ NCI CTEP Branch Chief and Disease Committee Chairs within NCI and NCTN Groups

+ Relevant Principal Investigators and External Scientific Experts

Essential Requirements

+ Advanced degree in science-related field, such as Pharmacology, Pharmacy, Medicine, or equivalent

+ Strong scientific and research background

+ >5 years managing programs in a team environment

+ Strong knowledge of medical strategy, clinical development, and medical science liaison areas

+ Ability to manage a diverse group of responsibilities

+ Ability to work effectively in a cross-functional team environment

+ Leadership abilities

+ Strategic influencing skills

+ Highly developed written and verbal communication skills

+ Well-developed initiative

+ Excellent project management skills

+ Strong organization and time management skills

+ Strong analytical and problem solving skills

+ Oncology disease experience

+ Working knowledge of FDA requirements

+ Excellent computer skills (Excel, Word, Power Point, etc.)

Next Steps

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity. If you know someone who would be a great fit, please share this posting with them.


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